We have been the DXA quality assurance site for many NIH-funded studies, CDC, and many more. Dr. Shepherd holds the patent that Hologic uses to measure body composition. He has also served as a past president of the ISCD and has either chaired or been a participant in all ISCD Position Development Conferences.

We work closely with the manufacturers and maintain workstations for Hologic and GE systems with the rights to use that software on scans other than those at our site. Our involvement in DXA quality assurance involves tasks such as,

  • Reviewing and revising DXA image data to ensure consistency by defining the same regions of interest within and among participants so that analyses of demographic differences and longitudinal change are assured that differences are not contaminated by differing definitions of body parts
  • Harmonizing data acquired for a Lunar DXA with data subsequently acquired from a Hologic scanner, so that investigators can examine changes in body composition and bone mineral density from different waves of participants, which may include creating a new master archive storage, cross-calibration equations, longitudinal correction and calibration of DXA data
  • Performing quality control checks on all DXA scans to insure correct participant alignment, appropriate location and accurate positioning of all regions of interest
  • Defining a protocol for ensuring consistency within and among participants’ DXA scan
  • Establishing procedures for continued quality control checks, reanalysis, and data generation for ongoing scans, which may include site manuals, training presentations/materials for site personnel, methods for validating DXA personnel

Below you will find past and current QA studies conducted at SRL, as well as QA-related publications. For inquiries, please contact us for more information.

Current Studies


Dual-energy x-ray absorptiometry (DXA) scan analysis and quality control review for NHANES 2018-2022

National Health and Nutrition Examination Survey (NHANES)

In this study, we are working on NHANES 2018-2022 to review the existing procedures manuals and update as needed by detailing procedures for obtaining the DXA scans for the protocol, perform longitudinal calibrations and cross-calibrations, and provide correction factors, if necessary. Specifically, we will be looking at DXA scans of the hip, spine, VFA spine, and whole body acquired at NHANES mobile examination centers. This data, along with data from similar studies will be used to examine age, sex, and racial/ethnic differences during the life cycle and to explore the relationship between body composition and behavioral factors such as diet and physical activity.

IMPAACT cover photo

IMPAACT 2009: Pharmacokinetics, Feasibility, Acceptability, and Safety of Oral Pre-Exposure Prophylaxis for Primary HIV Prevention during Pregnancy and Breast Feeding in Adolescents and Young Women and their Infants

IMPAACT 2010: Phase III Study of the Virologic Efficacy and Safety of Dolutegravir-Containing versus Efavirenz-Containing Antiretroviral Therapy Regimens in HIV-1-Infected Pregnant Women and their Infants

International Maternal Pediatric Adoloscent AIDS Clinical Trials (IMPAACT) Network

Our work with IMPAACT is divided between two studies: IMPAACT 2009 and IMPAACT 2010. IMPAACT 2009 is a study that evaluates daily oral Truvada PrEP in pregnant and lactating women. IMPAACT 2010 is a Phase III study of Virologic Efficacy and safety of Dolutegravir-containing versus Efavirenz-containing Antiretroviral therapy regimens in HIV-1-infected pregnant women and their infants. In both studies, our role is to monitor changes in bone mineral density (BMD), which will include central analysis of spine, femur, and whold body DXA scans. The IMPAACT 2009 study provides an important opportunity to study the effect of PrEP use and lactation on bone mass in young women who are yet to achieve peak bone mass. The IMPAACT 2010 study represents an important opportunity to learn more about the effects of the regimens on maternal and infant bone and renal outcomes.

Healthy Aging in Neighborhoods of Diversity across the Life Span (HANDLS)

HANDLS

The HANDLS study is a multidisciplinary, community-based, prospective longitudinal epidemiologic study examining the influence of race and socioeconomic status (SES) on the development of age-related health disparities among socioeconomically diverse African Americans and whites in Baltimore. This study investigates whether health disparities develop or persist due to differences in SES, differences in race, or their interaction. Similar to our work with NHANES, we are working on HANDLS to provide DXA analysis and quality control for their body composition and bone mineral density data. We are in the process of establishing procedures manuals and will review/update them as needed by detailing procedures for obtaining the DXA scans for the protocol, perform longitudinal calibrations and cross calibrations, and provide corrections factors, if necessary.

Extended use of NHANES Visceral Adiposity Cancer Risk Factors to GE Systems

The NHANES VAT measures will become the national reference data for VAT upon its release since there isn’t any other representative sample of VAT. However, the NHANES data was acquired on one make of DXA system, Hologic. VAT measures on Hologic DXA systems are substantially different than on GE systems, which complicate the pooling of VAT measures from different systems in multi-center clinical trials and make it difficult to compare VAT measures over time when a patient is scanned on different systems. Furthermore, with GE systems accounting for approximately 50% of the DXA clinical installation base, this means that half of the DXA users won’t be able to access the new NHANES VAT reference data. The objective of this study is to determine the relationship between Hologic and GE Lunar system for VAT measurements in children and adults, repost the NHANES VAT data in GE units, and provide cutoff points relevant for high risk of cancer and metabolic conditions.

Past Studies


Treatment Options for Type 2 Diabetes in Adolescents and Youth (TODAY)

National Institute of Diabetes and Digestive and Kidney Diseases

The TODAY study was a nationwide research study to compare the efficacy and safety of three interventions to treat adolescents and youth with type 2 diabetes. The primary outcome was time to treatment failure due to loss of glycemic control, defined as hemoglobin A1c >= 8% for 6 months.  Secondary outcomes included measures of beta cell function and insulin resistance, body composition, nutrition, physical activity and aerobic fitness, cardiovascular risk factors, microvascular complications, quality of life, and psychological outcomes.  The influence of individual and family behaviors on treatment response and the relative cost-effectiveness of the three treatment arms were also evaluated. This study has provided information fundamental to improving treatments and outcomes for youth with type 2 diabetes. Learn more.

National Institute of Child Health and Human Development

Bone Mineral Density in Childhood Study

BMDCS

The BMDCS (2001-2011) offered an unprecedented opportunity to identify predictors of the timing and magnitude of peak bone mass, a major determinant of osteoporosis in later adulthood. BMDCS investigators provided reference curves for bone accrual and linear growth velocity that are comparable to the Centers for Disease Control and Prevention linear growth and weight gain curves for children and adolescents. The reference curves generated by this carefully executed study provided the gold standard for normal bone accrual for generations to come. The study’s results enable practitioners to identify the adverse effects that chronic illness has on bone. Additionally, the results have clarified the effects that the timing of pubertal onset have on bone density and linear growth, as well as the need for height adjustment for dual-energy X-ray absorptiometry results in children. Learn more.

BeMyKids Study: Bone Mineral Accretion in Young Children

National Institute of Child Health and Human Development

Led by Dr. Heidi Kalkwarf, the BeMyKids study seeks to understand bone mineral accrual in children 1 to 5 years of age. A glaring deficit is the inability to evaluate bone health of children younger than 5 years due to lack of appropriate bone density reference data. This gap is problematic as there are numerous clinical conditions (e.g., neuromuscular disease, cancer, glucocorticoid treatment, extreme prematurity) that threaten bone health in this young age group. The findings from this study will facilitate medical care of children with chronic medical conditions that threaten bone health, and it will develop and validate novel methods for bone and body composition assessment in this age range. It will also add generalizable knowledge to enhance understanding of the growing skeleton, and its relationship to motor and somatic development. Learn more.

Safety Study of a Tenofovir-containing Drug Regimen for the Prevention of Mother-to-child Transmission of HIV and HBV – Tenofovir in Pregnancy (TiP) Study

TiP Study on the ClinicalTrials.gov site

The Tenofovir in Pregnancy (TiP) study was designed to test the safety of an antiretroviral combination containing TDF in pregnant women co-infected with HIV and HBV and their infants in Guangxi, China. The study’s objectives were to evaluate the renal, liver, and bone mineral density effects of TDF, administered from the second trimester of pregnancy, to women and their infants through a year postnatally. Learn more.

IMPAACT cover photo

IMPAACT P1084s: Maternal and Infant Monitoring for Evidence of Toxicity Related to Tenofovir Exposure: The Bone and Kidney Health Substudy of PROMISE

International Maternal Pediatric Adolescent AIDS Clinical Trials Network (IMPAACT)

P1084s is a nested, comparative substudy of HIV-1-infected women and their infants randomized in PROMISE (Promoting Maternal and Infant Survival Everywhere) to receive a maternal tenofovir-containing regimen or no maternal tenofovir-containing regimen during pregnancy or breastfeeding for prevention of mother-to-child transmission. The substudy was designed to examine bone, renal and growth outcomes of tenofovir exposure during pregnancy or during breastfeeding in 1077BF and 1077FF. Learn more.

DXA QA/QC Publications

Show all

36 entries « 1 of 2 »

Anderson, P A; Morgan, S L; Krueger, D; Zapalowski, C; Tanner, B; Jeray, K J; Krohn, K D; Lane, J P; Yeap, S S; Shuhart, C R; Shepherd, J

Use of Bone Health Evaluation in Orthopedic Surgery: 2019 ISCD Official Position Journal Article

In: J Clin Densitom, 22 (4), pp. 517-543, 2019, ISSN: 1094-6950 (Print) 1094-6950 (Linking).

Links | BibTeX | Tags: Absorptiometry, Bone Density, Bone Diseases, Consensus Development Conferences as Topic, diagnosis, Dual energy X-ray absorptiometry, Humans, methods, Orthopedic Procedures, Orthopedic surgery, Osteoporosis, Photon, Position statements, Screening criteria, standards, surgery

Brandt, K R; Scott, C G; Miglioretti, D L; Jensen, M R; Mahmoudzadeh, A P; Hruska, C; Ma, L; Wu, F F; Cummings, S R; Norman, A D; Engmann, N J; Shepherd, J A; Winham, S J; Kerlikowske, K; Vachon, C M

Automated volumetric breast density measures: differential change between breasts in women with and without breast cancer Journal Article

In: Breast Cancer Res, 21 (1), pp. 118, 2019, ISSN: 1465-542X (Electronic) 1465-5411 (Linking).

Links | BibTeX | Tags: Aged, Automation, Breast, Breast cancer, Breast Density, Breast Neoplasms, Case-Control Studies, diagnosis, diagnostic imaging, Early Detection of Cancer, Female, Humans, instrumentation, Mammography, methods, Middle Aged, Reproducibility of Results, Risk, Sensitivity and Specificity, Tissue asymmetry, Tumor Burden, Volumetric density

Hada, M; Oh, H; Pfeiffer, R M; Falk, R T; Fan, S; Mullooly, M; Pollak, M; Geller, B; Vacek, P M; Weaver, D; Shepherd, J; Wang, J; Fan, B; Mahmoudzadeh, A P; Malkov, S; Herschorn, S; Brinton, L A; Sherman, M E; Gierach, G L

Relationship of circulating insulin-like growth factor-I and binding proteins 1-7 with mammographic density among women undergoing image-guided diagnostic breast biopsy Journal Article

In: Breast Cancer Res, 21 (1), pp. 81, 2019, ISSN: 1465-542X (Electronic) 1465-5411 (Linking).

Links | BibTeX | Tags: Adult, Biomarkers, blood, Breast Density, Breast neoplasm, Breast Neoplasms, Cross-Sectional Studies, diagnosis, Female, Humans, Image-Guided Biopsy, Insulin-like growth factor, Insulin-Like Growth Factor Binding Proteins, Insulin-Like Growth Factor I, mammographic density, Mammography, metabolism, Middle Aged, Risk Factors

Houghton, L C; Jung, S; Troisi, R; LeBlanc, E S; Snetselaar, L G; Hylton, N M; Klifa, C; Horn, L Van; Paris, K; Shepherd, J A; Hoover, R N; Dorgan, J F

Pubertal timing and breast density in young women: a prospective cohort study Journal Article

In: Breast Cancer Res, 21 (1), pp. 122, 2019, ISSN: 1465-542X (Electronic) 1465-5411 (Linking).

Links | BibTeX | Tags: Adolescent, Adult, Body Mass Index, Body Size, Breast, Breast cancer, Breast Density, Breast Neoplasms, Child, diagnosis, diagnostic imaging, Female, growth & development, Humans, Magnetic Resonance Imaging, Menarche, methods, physiology, physiopathology, Prospective Studies, Puberty, Risk Factors, Sexual Maturation, Time Factors

Jankowski, L G; Warner, S; Gaither, K; Lenchik, L; Fan, B; Lu, Y; Shepherd, J

Cross-calibration, Least Significant Change and Quality Assurance in Multiple Dual-Energy X-ray Absorptiometry Scanner Environments: 2019 ISCD Official Position Journal Article

In: J Clin Densitom, 22 (4), pp. 472-483, 2019, ISSN: 1094-6950 (Print) 1094-6950 (Linking).

Links | BibTeX | Tags: Absorptiometry, Bone Density, Calibration, Consensus Development Conferences as Topic, cross calibration, diagnosis, Dual-energy X-ray absorptiometry, DXA QA/QC, Equipment Design, Health Care, Humans, instrumentation, least significant change, Medical, official positions, Osteoporosis, Photon, precision, Quality Assurance, Societies, standards

Mullooly, M; Puvanesarajah, S; Fan, S; Pfeiffer, R M; Olsson, L T; Hada, M; Kirk, E L; Vacek, P M; Weaver, D L; Shepherd, J; Mahmoudzadeh, A; Wang, J; Malkov, S; Johnson, J M; Hewitt, S M; Herschorn, S D; Sherman, M E; Troester, M A; Gierach, G L

Using Digital Pathology to Understand Epithelial Characteristics of Benign Breast Disease among Women Undergoing Diagnostic Image-Guided Breast Biopsy Journal Article

In: Cancer Prev Res (Phila), 12 (12), pp. 861-870, 2019, ISSN: 1940-6215 (Electronic) 1940-6215 (Linking).

Links | BibTeX | Tags: Adult, Age Factors, Aged, Algorithms, Breast, Breast Density, Breast Neoplasms, Computer-Assisted, Cross-Sectional Studies, diagnosis, diagnostic imaging, epidemiology, Epithelium, Female, Fibrocystic Breast Disease, Humans, Image Interpretation, Image-Guided Biopsy, Logistic Models, Mammography, methods, Middle Aged, pathology, Photon, prevention & control, Risk Factors

Rice, M S; Tamimi, R M; Bertrand, K A; Scott, C G; Jensen, M R; Norman, A D; Visscher, D W; Chen, Y Y; Brandt, K R; Couch, F J; Shepherd, J A; Fan, B; Wu, F F; Ma, L; Collins, L C; Cummings, S R; Kerlikowske, K; Vachon, C M

Does mammographic density mediate risk factor associations with breast cancer? An analysis by tumor characteristics Journal Article

In: Breast Cancer Res Treat, 170 (1), pp. 129-141, 2018, ISSN: 1573-7217 (Electronic) 0167-6806 (Linking).

Links | BibTeX | Tags: Adult, Aged, Biomarkers, Breast, Breast cancer, Breast Density, Breast Neoplasms, classification, diagnosis, diagnostic imaging, ErbB-2, Estrogen, Female, genetics, Humans, mammographic density, Mammography, Middle Aged, pathology, Pregnancy, Progesterone, Receptor, Receptors, Risk Factors, Tumor

Kerlikowske, K; Ma, L; Scott, C G; Mahmoudzadeh, A P; Jensen, M R; Sprague, B L; Henderson, L M; Pankratz, V S; Cummings, S R; Miglioretti, D L; Vachon, C M; Shepherd, J A

Combining quantitative and qualitative breast density measures to assess breast cancer risk Journal Article

In: Breast Cancer Res, 19 (1), pp. 97, 2017, ISSN: 1465-542X (Electronic) 1465-5411 (Linking).

Links | BibTeX | Tags: Aged, Breast, Breast cancer risk, Breast Density, Breast Neoplasms, Case-Control Studies, Dense volume, diagnosis, diagnostic imaging, Early Detection of Cancer, epidemiology, Female, Humans, methods, Middle Aged, Neoplasm Staging, Odds Ratio, pathology, Public Health Surveillance, Risk Assessment, Risk Factors

Lewiecki, E M; Bilezikian, J P; Bukata, S V; Camacho, P; Clarke, B L; McClung, M R; Miller, P D; Shepherd, J

Proceedings of the 2016 Santa Fe Bone Symposium: New Concepts in the Management of Osteoporosis and Metabolic Bone Diseases Journal Article

In: J Clin Densitom, 20 (2), pp. 134-152, 2017, ISSN: 1094-6950 (Print) 1094-6950 (Linking).

Links | BibTeX | Tags: Absorptiometry, antagonists & inhibitors, blood, Bone Density Conservation Agents, Bone Diseases, Cathepsin K, Chronic Disease, complications, Denosumab, diagnosis, diagnostic imaging, Drug Discovery, drug therapy, dxa, Echo, etiology, Fracture Healing, genetics, Humans, Hyperphosphatemia, Hypophosphatemia, Metabolic, metabolism, Osteoporosis, Osteoporotic Fractures, Parathyroid Hormone-Related Protein, Phosphorus, Photon, Practice Guidelines as Topic, RANK Ligand, Rare Diseases, Receptor Activator of Nuclear Factor-kappa B, therapeutic use, Translational Medical Research

Brandt, K R; Scott, C G; Ma, L; Mahmoudzadeh, A P; Jensen, M R; Whaley, D H; Wu, F F; Malkov, S; Hruska, C B; Norman, A D; Heine, J; Shepherd, J; Pankratz, V S; Kerlikowske, K; Vachon, C M

Comparison of Clinical and Automated Breast Density Measurements: Implications for Risk Prediction and Supplemental Screening Journal Article

In: Radiology, 279 (3), pp. 710-9, 2016, ISSN: 1527-1315 (Electronic) 0033-8419 (Linking).

Links | BibTeX | Tags: 3cb, 80 and over, Adult, Aged, Automation, Breast Density, Breast Neoplasms, diagnosis, Early Detection of Cancer, Female, Forecasting, Humans, methods, Middle Aged, Risk, three-compartment breast, Young Adult

Mahmoudzadeh, Amir Pasha; Malkov, Serghei; Hinton, Benjamin; Sprague, Brian; Kerlikowske, Karla; Shepherd, John

Do Women with Low Breast Density Have Regionally High Breast Density? Conference

Proceedings of the 13th International Workshop on Breast Imaging - Volume 9699, Springer-Verlag, 2016.

Links | BibTeX | Tags: 3cb, Artifacts, Breast, Breast Density, Breast Neoplasms, cancer, Case-Control Studies, Computer-Assisted, detectability, diagnosis, diagnostic imaging, Early Detection of Cancer, Female, Humans, Image Processing, interval, Mammography, masking, methods, Prognosis, Risk Assessment, Risk Factors, three-compartment breast

Malkov, S; Shepherd, J A; Scott, C G; Tamimi, R M; Ma, L; Bertrand, K A; Couch, F; Jensen, M R; Mahmoudzadeh, A P; Fan, B; Norman, A; Brandt, K R; Pankratz, V S; Vachon, C M; Kerlikowske, K

Mammographic texture and risk of breast cancer by tumor type and estrogen receptor status Journal Article

In: Breast Cancer Res, 18 (1), pp. 122, 2016, ISSN: 1465-542X (Electronic) 1465-5411 (Linking).

Links | BibTeX | Tags: Aged, Body Mass Index, Breast Density, Breast Neoplasms, Carcinoma, Case-Control Studies, diagnosis, diagnostic imaging, Estrogen, Female, Fractals, Humans, Intraductal, Logistic Models, Mammography, Mass Screening, metabolism, methods, Middle Aged, Noninfiltrating, Receptors, Risk Assessment, Risk Factors

Bodelon, C; Heaphy, C M; Meeker, A K; Geller, B; Vacek, P M; Weaver, D L; Chicoine, R E; Shepherd, J A; Mahmoudzadeh, A P; Patel, D A; Brinton, L A; Sherman, M E; Gierach, G L

Leukocyte telomere length and its association with mammographic density and proliferative diagnosis among women undergoing diagnostic image-guided breast biopsy Journal Article

In: BMC Cancer, 15 , pp. 823, 2015, ISSN: 1471-2407 (Electronic) 1471-2407 (Linking).

Links | BibTeX | Tags: 3cb, abnormalities, Adult, Aged, Breast Density, Breast Neoplasms, Cross-Sectional Studies, diagnosis, Female, genetics, Human, Humans, Image-Guided Biopsy, Leukocytes, Mammary Glands, metabolism, Middle Aged, Neoplasm Staging, Risk Factors, Telomere, three-compartment breast

Engelke, K; Lang, T; Khosla, S; Qin, L; Zysset, P; Leslie, W D; Shepherd, J A; Schousboe, J T

Clinical Use of Quantitative Computed Tomography (QCT) of the Hip in the Management of Osteoporosis in Adults: the 2015 ISCD Official Positions-Part I Journal Article

In: J Clin Densitom, 18 (3), pp. 338-58, 2015, ISSN: 1094-6950 (Print) 1094-6950 (Linking).

Links | BibTeX | Tags: Absorptiometry, Acetabulum, Adult, Bone, Bone Density, Bone mineral density (BMD), complications, Consensus, diagnosis, diagnostic imaging, etiology, Femur, Fractures, Humans, Medical, Osteoporosis, Photon, Position, Practice Guidelines as Topic, Proximal femur, Quantitative computed tomography (QCT), Risk Assessment, Societies, Tomography, X-Ray Computed

Engelke, K; Lang, T; Khosla, S; Qin, L; Zysset, P; Leslie, W D; Shepherd, J A; Schousboe, J T

Clinical Use of Quantitative Computed Tomography-Based Advanced Techniques in the Management of Osteoporosis in Adults: the 2015 ISCD Official Positions-Part III Journal Article

In: J Clin Densitom, 18 (3), pp. 393-407, 2015, ISSN: 1094-6950 (Print) 1094-6950 (Linking).

Links | BibTeX | Tags: Absorptiometry, Acetabulum, Adult, Asynchronous and internal calibration, Bone, Bone Density, Calibration, complications, Consensus, diagnosis, diagnostic imaging, etiology, Femur, Fractures, Humans, Lumbar Vertebrae, Mass Screening, Medical, methods, opportunistic screening, Osteoporosis, Photon, Practice Guidelines as Topic, Quantitative computed tomography (QCT), Risk Assessment, Societies, statistical parameter mapping (SPM), Tomography, X-Ray Computed

Zysset, P; Qin, L; Lang, T; Khosla, S; Leslie, W D; Shepherd, J A; Schousboe, J T; Engelke, K

Clinical Use of Quantitative Computed Tomography-Based Finite Element Analysis of the Hip and Spine in the Management of Osteoporosis in Adults: the 2015 ISCD Official Positions-Part II Journal Article

In: J Clin Densitom, 18 (3), pp. 359-92, 2015, ISSN: 1094-6950 (Print) 1094-6950 (Linking).

Links | BibTeX | Tags: Absorptiometry, Acetabulum, Adult, Bone, Bone Density, complications, Consensus, diagnosis, diagnostic imaging, etiology, Femur, finite element analysis, finite element analysis (FEA), Fractures, Humans, Lumbar Vertebrae, Medical, Osteoporosis, Photon, Position, Practice Guidelines as Topic, Quantitative computed tomography (QCT), Risk Assessment, Societies, Tomography, X-Ray Computed

Cheddad, A; Czene, K; Shepherd, J A; Li, J; Hall, P; Humphreys, K

Enhancement of mammographic density measures in breast cancer risk prediction Journal Article

In: Cancer Epidemiology, Biomarkers & Prevention, 23 (7), pp. 1314-23, 2014, ISSN: 1538-7755 (Electronic) 1055-9965 (Linking).

Links | BibTeX | Tags: abnormalities, Aged, Area Under Curve, Breast Density, Breast Neoplasms, Computer-Assisted, diagnosis, diagnostic imaging, DNA-Binding Proteins, Female, genetics, Genotype, Human, Humans, Mammary Glands, Mammography, methods, Middle Aged, Pectoralis Muscles, Polymorphism, Radiographic Image Enhancement, Radiographic Image Interpretation, Risk Factors, ROC Curve, Single Nucleotide, Transcription Factors

Drukker, K; Duewer, F; Giger, M L; Malkov, S; Flowers, C I; Joe, B; Kerlikowske, K; Drukteinis, J S; Li, H; Shepherd, J A

Mammographic quantitative image analysis and biologic image composition for breast lesion characterization and classification Journal Article

In: Medical Physics, 41 (3), pp. 031915, 2014, ISSN: 2473-4209 (Electronic) 0094-2405 (Linking).

Links | BibTeX | Tags: 3cb, Automation, Biopsy, Breast, Breast Neoplasms, chemistry, Computer-Assisted, diagnosis, diagnostic imaging, Female, Humans, Lipids, Mammography, methods, pathology, Probability, Prospective Studies, Radiographic Image Interpretation, ROC Curve, three-compartment breast, Water

Malkov, S; Shepherd, J

Combining 3D optical imaging and dual energy absorptiometry to measure three compositional components Journal Article

In: Proc SPIE Int Soc Opt Eng, 8937 , pp. 893714, 2014, ISSN: 0277-786X (Print) 0277-786X (Linking).

Links | BibTeX | Tags: 3cb, 80 and over, Adult, Aged, Biopsy, Breast Diseases, Computer-Assisted, diagnosis, diagnostic imaging, Differential, Female, Humans, Mammography, methods, Middle Aged, pathology, Predictive Value of Tests, Prospective Studies, Radiographic Image Interpretation, three-compartment breast

Dorgan, J F; Klifa, C; Deshmukh, S; Egleston, B L; Shepherd, J A; O., Jr. Kwiterovich P.; Horn, L Van; Snetselaar, L G; Stevens, V J; Robson, A M; Lasser, N L; Hylton, N M

Menstrual and reproductive characteristics and breast density in young women Journal Article

In: Cancer Causes Control, 24 (11), pp. 1973-83, 2013, ISSN: 1573-7225 (Electronic) 0957-5243 (Linking).

Links | BibTeX | Tags: administration & dosage, Adult, Age Factors, anatomy & histology, Breast, Breast Neoplasms, Contraception, Contraceptives, Cross-Sectional Studies, diagnosis, Female, Follow-Up Studies, Hormonal, Humans, Magnetic Resonance Imaging, Menarche, Menstruation, methods, Multivariate Analysis, Oral, physiology, prevention & control, Reproduction, statistics & numerical data, Surveys and Questionnaires, Time Factors

Wilson, J P; Fan, B; Shepherd, J A

Total and regional body volumes derived from dual-energy X-ray absorptiometry output Journal Article

In: J Clin Densitom, 16 (3), pp. 368-373, 2013, ISSN: 1094-6950 (Print) 1094-6950 (Linking).

Links | BibTeX | Tags: 4-Compartment body composition, Absorptiometry, Adp, Adult, BodPod, Body Composition, Bone Density, diagnosis, dxa, Female, Humans, Impedance, Male, methods, Obesity, Photon, physiology, Plethysmography, Retrospective Studies, volume

Katzman, W; Cawthon, P; Hicks, G E; Vittinghoff, E; Shepherd, J; Cauley, J A; Harris, T; Simonsick, E M; Strotmeyer, E; Womack, C; Kado, D M

Association of spinal muscle composition and prevalence of hyperkyphosis in healthy community-dwelling older men and women Journal Article

In: J Gerontol A Biol Sci Med Sci, 67 (2), pp. 191-5, 2012, ISSN: 1758-535X (Electronic) 1079-5006 (Linking).

Links | BibTeX | Tags: Age Factors, Aged, Body Composition, Bone Density, Cross-Sectional Studies, diagnosis, epidemiology, Female, Humans, Kyphosis, Male, Men's Health, Muscle, Muscular Diseases, physiology, physiopathology, Prevalence, Reference Values, Risk Factors, Sex Distribution, Sex Factors, Skeletal, Spine, United States

Wilson, J P; Mulligan, K; Fan, B; Sherman, J L; Murphy, E J; Tai, V W; Powers, C L; Marquez, L; Ruiz-Barros, V; Shepherd, J A

Dual-energy X-ray absorptiometry-based body volume measurement for 4-compartment body composition Journal Article

In: Am J Clin Nutr, 95 (1), pp. 25-31, 2012, ISSN: 1938-3207 (Electronic) 0002-9165 (Linking).

Links | BibTeX | Tags: Absorptiometry, Adipose Tissue, Adult, Biological, Body Composition, Body Size, diagnosis, diagnostic imaging, Female, Humans, Male, methods, Middle Aged, Models, Obesity, Photon, Plethysmography, Reproducibility of Results

Maskarinec, G; Morimoto, Y; Daida, Y; Shepherd, J; Novotny, R

A comparison of breast density measures between mothers and adolescent daughters Journal Article

In: BMC Cancer, 11 , pp. 330, 2011, ISSN: 1471-2407 (Electronic) 1471-2407 (Linking).

Links | BibTeX | Tags: Absorptiometry, Adipose Tissue, Adolescent, Adult, Breast, Breast Neoplasms, Child, diagnosis, diagnostic imaging, Family Health, Female, genetics, Humans, metabolism, methods, Middle Aged, Mothers, Photon, Pilot Projects, Reproducibility of Results, Sensitivity and Specificity

Flegal, K M; Ogden, C L; Yanovski, J A; Freedman, D S; Shepherd, J A; Graubard, B I; Borrud, L G

High adiposity and high body mass index-for-age in US children and adolescents overall and by race-ethnic group Journal Article

In: Am J Clin Nutr, 91 (4), pp. 1020-6, 2010, ISSN: 1938-3207 (Electronic) 0002-9165 (Linking).

Links | BibTeX | Tags: Absorptiometry, Adiposity, Adolescent, Adult, Body Mass Index, Child, diagnosis, epidemiology, ethnology, Female, Hispanic Americans, Humans, Male, Mass Screening, methods, Obesity, Photon, Prevalence, Reference Values, United States, Young Adult

36 entries « 1 of 2 »